Investigation of biomedical inner microstructures with hard X-ray phase-contrast imaging

Hard X-ray Phase-Contrast Imaging (HX-PCI) is a new and valuable method that may provide information of the inner parts of an opaque object. Previous reports demonstrated its applicability in soft and hard tissue imaging. Here we provide further evidence for improved image quality and the effective...

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Published in:Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment Accelerators, spectrometers, detectors and associated equipment, 2007-09, Vol.580 (1), p.610-613
Main Authors: Shu, Hang, Zhu, Peiping, Chen, Bo, Liu, Bo, Yin, Hongxia, Li, Enrong, Liu, Yijin, Wang, Junyue, Yuan, Qingxi, Huang, Wanxia, Fang, Shouxian, Wu, Ziyu
Format: Article
Language:English
Subjects:
Cochlea
DEI
DEI-CT
Hard X-ray imaging
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Summary:Hard X-ray Phase-Contrast Imaging (HX-PCI) is a new and valuable method that may provide information of the inner parts of an opaque object. Previous reports demonstrated its applicability in soft and hard tissue imaging. Here we provide further evidence for improved image quality and the effective capability to distinguish inner microstructures in real biomedical systems such as cochlea. Experiments performed both at the 4W1A beamline of the Beijing Synchrotron Radiation Facility (BSRF) and at the Taiwan National Synchrotron Radiation Research Center (NSRRC) clearly show details of samples’ inner microstructure with a resolution of a few microns. The improved spatial resolution is a relevant achievement for future improved understanding and clinical trials.
ISSN:0168-9002
1872-9576
DOI:10.1016/j.nima.2007.05.022