1 kHz laser accelerated electron beam feasible for radiotherapy uses: A PIC–Monte Carlo based study

• Published in: Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment Accelerators, spectrometers, detectors and associated equipment, 2021-01, Vol.987, p.164841, Article 164841
• Main Authors: Polanek, R., Hafz, Nasr A.M., Lécz, Zs, Papp, D., Kamperidis, C., Brunner, Sz, Szabó, E.R., Tőkés, T., Hideghéty, K.
• Format: Article
• Language: English
• Subjects: Electron radiotherapy; LWFA acceleration
• ISSN: 0168-9002; 1872-9576
• DOI: 10.1016/j.nima.2020.164841

Laser wakefield acceleration (LWFA) offers a promising compact solution for the production of high and very high energy electron (VHEE) beams, which have an ultrashort pulse duration with a high instantaneous dose rate and small source size. These unique properties are of radiobiological as well as clinical interest. In this paper we focus on the potential application of high repetition rate LWFA electron beams for radiobiology and radiotherapy. On the basis of particle-in-cell (PIC) and Monte Carlo simulations we propose that, using a commercially available 1kHz laser system one can generate electron beams with 35.7MeV mean energy and 3pC electron bunch charge at 1kHz repetition rate to deliver a dose rate of 18Gy/min, which could be extremely useful for real radiotherapy applications. Thanks to the high repetition rate, dose delivery can be performed with high precision making this system a potential alternative to conventional clinical electron accelerators.