Spironolactone, a therapeutic alternative in the treatment of diffuse retinal pigment epitheliopathy

Abstract Case report Two cases are presented of patients with chronic diffuse epitheliopathy (CDE) that showed a favourable response when treated with spironolactone. The first patient had regions of neurosensory detachment (DNS) and the second, multiple DNS, secondary intra-retinal cysts and retina...

Full description

Saved in:
Bibliographic Details
Published in:Archivos de la Sociedad Española de Oftalmología (English ed.) 2016-12, Vol.91 (12), p.599-603
Main Authors: Ángel-Pereira, D, Rocha-Cabrera, P, Cordovés-Dorta, L, Losada Castillo, M.J, Blasco Alberto, A, Abreu Reyes, J.A
Format: Article
Language:English
Subjects:
Aldosterona
Aldosterone
Antagonistas
Antagonists
Chronic
Crónica
Diffuse
Difusa
Epiteliopatía
Epitheliopathy
Espironolactona
Ophthalmology
Receptor
Receptores
Spironolactone
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Case report Two cases are presented of patients with chronic diffuse epitheliopathy (CDE) that showed a favourable response when treated with spironolactone. The first patient had regions of neurosensory detachment (DNS) and the second, multiple DNS, secondary intra-retinal cysts and retinal pigment epithelium detachment. Discussion After treatment with spironolactone, both patients showed a visual acuity improvement and structural changes (reduced neurosensory retinal detachment and cystoid degeneration). Aldosterone receptor agonists (ARA) used for persistent forms of chronic central serous chorioretinopathy show encouraging results and could represent a therapeutic alternative for CDE.
ISSN:2173-5794
2173-5794
DOI:10.1016/j.oftale.2016.05.005