ORAL MANIFESTATIONS OF OVERLAP SYNDROME ASSOCIATED WITH SYSTEMIC LUPUS ERYTHEMATOUS: A CASE REPORT

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2020-09, Vol.130 (3), p.e119-e119
• Main Authors: OLIVEIRA, CATARINA RODRIGUES ROSA DE, PANJWANI, CAMILA MARIA BEDERRIBEIRO GIRISH, SILVA, CLAYTON CLENISSON DE CARVALHO, SANTOS, VANESSA DE CARLA BATISTA DOS, ABREU, EULINA MARIA VIEIRA DE, CINTRA, MARIA LETÍCIA, FERREIRA, SONIA MARIA SOARES
• Format: Article
• Language: English
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2020.04.046

Overlap syndrome (OS) associated with systemic lupus erythematosus (SLE) is characterized for clinical signs synchronic with histopathologic characteristics of lichen planus (LP). We report a case of a female, 39 years old, diagnosed with SLE and melanoderma, who had lesions in her mouth. Intra-oral examination showed whitish plaques in her bilateral buccal mucosa. Clinical diagnosis hypothesis were oral LP (OLP) and SLE. After biopsy, an allergic contact process was diagnosed through histopathology, and amalgam restorations related to the lesion were removed. Three years later the patient returned with other lesions, and a biopsy revealed bullous lesions that were referred to treatment. However, in spite of the established treatment, the patient has returned later with erosive lesions diagnosed through biopsy and direct immunofluorescence as erosive OLP. Corticosteroids were prescribed, and the patient remained without lesions after 2 years’ follow-up. This case reinforces that OS is challenging in diagnosis and treatment and involves several professionals to manage it.