IMMUNOFLUORESCENCE AS A DIAGNOSTIC TOOL FOR ORAL LICHEN PLANUS

A 40-year-old female patient without systemic diseases and without the use of medication presented complaints of painful and bleeding wounds on the mouth. On physical examination, multiple bleeding ulcers on the tongue, lip, and jugal mucosa were observed, some with fibrinopurulent pseudomembrane. L...

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Published in:Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2020-09, Vol.130 (3), p.e196-e196
Main Authors: CERQUEIRA, MALU BASTOS SOUZA, RAMALHO, LUCIANA MARIA PEDREIRA, ARRUDA, SÉRGIO, MELO, LEONARDO DE ARAÚJO, PEREIRA, MANOELA CARRERA MARTINEZ CAVALCANTE
Format: Article
Language:English
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Summary:A 40-year-old female patient without systemic diseases and without the use of medication presented complaints of painful and bleeding wounds on the mouth. On physical examination, multiple bleeding ulcers on the tongue, lip, and jugal mucosa were observed, some with fibrinopurulent pseudomembrane. Laboratory tests excluded autoimmune diseases, venereal diseases, and anemias. Excisional biopsy was performed to exclude the diagnosis of bullous lesions. Anatomohistopathologic examination demonstrated areas of ulcerated connective tissue with chronic inflammatory infiltrate. Immunofluorescence indicated the presence of fibrinogen deposits, closing the diagnosis as oral lichen planus. After the biopsy, the patient took 8 months to return to the service. At this moment, she presented with the same oral condition plus pruritic, violaceous lesions on the skin with a predilection for upper and lower limbs. Treatment with prednisone 60 mg/d was instituted, and the patient is in clinical follow-up.
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2020.04.409