EPIDERMOID CARCINOMA—CLEAR CELL VARIANT: CASE REPORT

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2022-09, Vol.134 (3), p.e181-e181
• Main Authors: Bastos, Yann Victor Paiva, De Albuquerque, Ricardo Luiz Cavacanti, De Oliveira, Catarina Rodrigues Rosa, De Andrade, Renata, Panjwani, Camila Maria Beder Ribeiro Girish, De Carvalho Silva, Clayton Clenisson, Ferreira, Sonia Maria Soares
• Format: Article
• Language: English
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2022.01.534

The aim of this study is to report the case of a 75-year-old dark-skinned male patient symptomatic lesion in the region of the alveolar ridge with extension to the oral floor with a 4-month evolution who attended the stomatology service reporting “to see the wound.” On extraoral examination, palpable lymph nodes in the submandibular region were noted. On intraoral examination, a tumor lesion, reddish, in the lower anterior alveolar ridge with infiltration to the oral floor, an ulcerated surface, firm consistency, and diffuse limits was noted. The clinical diagnosis was squamous cell carcinoma. An incisional biopsy was performed, and histopathologic analysis of the specimens showed the absence of tumor emboli in lymphatic vessels and of perineural invasion. Periodic acid-Schiff stains showed diastasis-resistant positivity and immunohistochemical reactions were positive for AE1/AE3 and p63 but negative for a-smooth muscle actin, confirming squamous cell carcinoma clear cell variant. The patient was referred to the oncologist.