DESMOPLASTIC FIBROMA OF GNATHIC BONES: A SYSTEMATIC REVIEW

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2023-07, Vol.136 (1), p.e35-e35
• Main Authors: STELTER, Grazielle Oliveira, RODRIGUES, Wictor Nogueira, SCHUCH, Lauren Frenzel, LOUREIRO, Felippe José Almeida, SILVEIRA, Felipe Martins, MARTINS, Marco Antônio Trevizani, MARTINS, Manoela Domingues
• Format: Article
• Language: English
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.03.081

To analyze the available data regarding desmoplastic fibroma (DF) into a systematic review to integrate the demographic, clinical and histopathological features, treatment, and recurrence of this condition. The present study was conducted based on PRISMA statement. An electronic search was undertaken in August 2021 in four databases. The eligibility criteria were restricted to case reports, case series. and cross-sectional studies. Eighty-one articles met the eligibility criteria, yielding 125 cases of DF. Women (60.8%) were more affected, with a mean age of 19.1 years (SD±16.7). In relation to the anatomical site, 69.4% lesions were found in posterior mandible, with a bulging tumor clinical appearance. Most lesions were asymptomatic (85.9%) with a mean evolution time of 11 months. Radiologically, the tumor is described as a radiolucent (92,4%) multilocular (70.5%) lesion, presenting defined borders (35.5%) as well as causing bone expansion (28.2%). Resection (53.1%) and enucleation (14.3%) were the treatment choice in most cases. Recurrence was observed in 11.6% of the cases, with resection being the treatment of choice (100%). DF is a rare bone tumor with a challenging diagnosis and treatment. This study provides information that could be helpful for the diagnosis and management of this condition.