AMELOBLASTIC CARCINOMA OF THE MANDIBLE: A CASE REPORT

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2024-06, Vol.137 (6), p.e250-e250
• Main Authors: BETIATTO, Daiane, QUEIROZ, Aline, FREDES, Carolina, LOPES-MELLO, Thaís, QUINDERÉ, Elvira Rachel Carvalho Ferreira, UYEDA, Daniel Kazutoyo Paixão, TRIERVEILER, Marília
• Format: Article
• Language: English
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.12.497

Ameloblastic carcinoma is an infrequent malignant epithelial neoplasm. A 52-year-old Caucasian male patient presented with an expansive lesion in the posterior region of the right mandible. During clinical examination, a purplish nodule was observed in the region of the right mandibular body and ramus, which was painful upon palpation. Computed tomography scans revealed a single-chamber, low-density lesion in the posterior mandibular area with lingual expansion and areas of bone fenestration. An incisional biopsy was conducted, and the histopathological report initially indicated ameloblastoma. Subsequently, a surgical excision of the lesion was planned, and the mandibular resection specimen was sent to our pathology service. Upon examination, the specimen revealed a malignant epithelial odontogenic neoplasm that vaguely resembled ameloblastoma. This neoplasm was characterized by cell proliferation arranged in various patterns, such as bone trabeculae, densely cellular solid islands, cords, and nests, leading to a revised histopathological diagnosis of ameloblastic carcinoma. The patient was then referred to the oncology service to proceed with the necessary treatment.