Investigation of recurrent infection

Abstract Repeated episodes of infection are required for the development of a competent immune system and, therefore, are an expected norm in early childhood. Although most children with recurrent infection have normal immunity and do not have serious underlying disease, early and accurate detection...

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Bibliographic Details
Published in:Paediatrics and child health 2008-11, Vol.18 (11), p.483-490
Main Authors: Hughes, Stephen, Clark, Julia
Format: Article
Language:English
Subjects:
antibody deficiency
HIV infection
immunodeficiency
infectious diseases
laboratory investigation
Pediatrics
recurrent infection
severe combined immunodeficiency
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Summary:Abstract Repeated episodes of infection are required for the development of a competent immune system and, therefore, are an expected norm in early childhood. Although most children with recurrent infection have normal immunity and do not have serious underlying disease, early and accurate detection of immunodeficient children is essential for delivery of optimised care. This review aims to provide a framework for rational investigation.
ISSN:1751-7222
1878-206X
DOI:10.1016/j.paed.2008.07.014