Isolation and structure elucidation of siliendines A‒D, new β-carboline alkaloids from Silene seoulensis

[Display omitted] •Eight compounds, including four new β-carboline alkaloids were isolated from the aerial parts of Silene seoulensis.•Compounds 5 and 7 were reported from Silene genus for the first time.•Structure elucidation was based on spectroscopic techniques (1D-, 2D-NMR, and HRMS experiments)...

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Bibliographic Details
Published in:Phytochemistry letters 2020-04, Vol.36, p.58-62
Main Authors: Seo, Changon, Shin, Hyoung Seok, Lee, Ji Eun, Jung, Yeon Woo, Kim, Jin Kyu, Kwon, Jin Gwan, Jeong, Wonsik, Choi, Chun Whan, Oh, Joa Sub, Hong, Seong Su
Format: Article
Language:English
Subjects:
Caryophyllaceae
Silene seoulensis
Siliendine
β-Carboline alkaloid
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Summary:[Display omitted] •Eight compounds, including four new β-carboline alkaloids were isolated from the aerial parts of Silene seoulensis.•Compounds 5 and 7 were reported from Silene genus for the first time.•Structure elucidation was based on spectroscopic techniques (1D-, 2D-NMR, and HRMS experiments). Four new β-carboline alkaloids, siliendines A–D (1‒4), and four known metabolites (5–8) were isolated from the ethanolic extract of the aerial parts of Silene seoulensis using various chromatographic methods. The structures of the new compounds were established using multiple spectroscopic approaches, with techniques such as HRESIMS and NMR, which included HSQC and HMBC. The known compounds were identified by comparing their spectra with those of the reported compounds.
ISSN:1874-3900
1876-7486
DOI:10.1016/j.phytol.2020.01.010