New flavones from the stems of Dracaena angustifolia

[Display omitted] •Four new flavones were isolated from the stems of Dracaena angustifolia.•The new compounds were elucidated by spectroscopic data and quantum calculations.•The anti-inflammatory activity of the new compounds was evaluated. Four new flavone derivatives (1–4), together with six known...

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Bibliographic Details
Published in:Phytochemistry letters 2020-04, Vol.36, p.115-119
Main Authors: Zhao, Ting, Nong, Xu-Hua, Zhang, Bin, Tang, Min-Min, Huang, Dan-Yu, Wang, Jia-Li, Xiao, Jun-Lu, Chen, Guang-Ying
Format: Article
Language:English
Subjects:
Anti-inflammatory activity
Dracaena angustifolia
Flavone
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Summary:[Display omitted] •Four new flavones were isolated from the stems of Dracaena angustifolia.•The new compounds were elucidated by spectroscopic data and quantum calculations.•The anti-inflammatory activity of the new compounds was evaluated. Four new flavone derivatives (1–4), together with six known flavones (5-10), were isolated from the stems of Dracaena angustifolia. The complete structures of new compounds were elucidated by analyses of spectroscopic data and quantum chemistry calculations. Compounds 2, 9 and 10 displayed weak anti-inflammatory activity with IC50 values of 45, 33 and 61 μM, respectively.
ISSN:1874-3900
1876-7486
DOI:10.1016/j.phytol.2020.01.025