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Compactibility and compressibility studies of Assam Bora rice starch

A comparison study was made on the powder flow characteristics, tableting properties of experimental Assam Bora rice starch, obtained from the variety Aghuni Bora of Oryza sativa and the mechanical properties of tablets made up of it with those of official Starch 1500®. The influences of physical an...

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Bibliographic Details
Published in:Powder technology 2012-07, Vol.224, p.281-286
Main Authors: Ahmad, Mohammad Zaki, Akhter, Sohail, Anwar, Mohammed, Rahman, Mahfoozur, Siddiqui, Mohammad Ahsan, Ahmad, Farhan Jalees
Format: Article
Language:English
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Summary:A comparison study was made on the powder flow characteristics, tableting properties of experimental Assam Bora rice starch, obtained from the variety Aghuni Bora of Oryza sativa and the mechanical properties of tablets made up of it with those of official Starch 1500®. The influences of physical and geometrical properties of both the starch were evaluated with regards to their compression properties. It has been found that Assam Bora rice starch reflects better physical characteristics such as higher bulk and tap densities, less porosity, better powder packing ability, minimum lubricant sensitivity, large surface area and improved flowability. Apart from that the mechanical properties, such as toughness and Young's modulus of Assam Bora rice starch were also compared with that of Starch 1500®. It has been also brought into result that compactibility of Assam Bora rice starch was not affected by the blending time. Further compaction properties of the experimental starch were evaluated by using Kawakita and Heckel equations and compared well with those of Starch 1500®. The result obtained shows that it mainly deforms by plastic deformation. Their onset of plastic deformation and strain rate sensitivity as compared to that of Starch 1500® demonstrates its potential use as a direct compression filler-binders. The tableting and mechanical properties of experimental Assam Bora rice starch were characterized and compared with official Starch 1500®. Here we concluded that compactibility of Assam Bora rice starch was not affected by the blending time. Assam Bora rice starch could be useful as a directly compressible vehicle in formulation to produce tablet with desired mechanical properties. [Display omitted]
ISSN:0032-5910
1873-328X
DOI:10.1016/j.powtec.2012.03.004