Systematic Analysis of Injectable Materials and 3D Rapid Prototyped Magnetic Scaffolds: From CNS Applications to Soft and Hard Tissue Repair/Regeneration

Over the past years, polymer-based materials have attracted research interest in the field of tissue repair and regeneration. As reported in literature, different injectable systems have been proposed, trying to reduce surgical invasiveness. In a first step of the current research, the rheological a...

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Bibliographic Details
Published in:Procedia engineering 2013, Vol.59, p.233-239
Main Authors: Russo, Teresa, D’Amora, Ugo, Gloria, Antonio, Tunesi, Marta, Sandri, Monica, Rodilossi, Serena, Albani, Diego, Forloni, Gianluigi, Giordano, Carmen, Cigada, Alberto, Tampieri, Anna, De Santis, Roberto, Ambrosio, Luigi
Format: Article
Language:English
Subjects:
Injectable Materials
Magnetic Scaffolds
Nanocomposites
Rapid Prototyping
Rheology
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Summary:Over the past years, polymer-based materials have attracted research interest in the field of tissue repair and regeneration. As reported in literature, different injectable systems have been proposed, trying to reduce surgical invasiveness. In a first step of the current research, the rheological and functional features of injecatble hydrogel-based materials for central nervous system applications or soft tissue regeneration (collagen/PEG semi-IPNs) as well as for hard tissue engineering (alginate/iron-doped hydroxyapatite) were evaluated. Then, the study was also devoted to the development of 3D nanocomposite poly(ɛ- caprolactone)/iron-doped hydroxyapatite scaffolds for bone tissue engineering, providing a preliminary approach to assess magnetic attraction forces.
ISSN:1877-7058
1877-7058
DOI:10.1016/j.proeng.2013.05.116