The influence of process parameters on the physical characteristics of ceramic microneedles, evaluated using a factorial design

The paper presents the application of the factorial Design of Experiments (DoE) to evaluate the influence of process parameters on the physical characteristics of ceramic microneedles (CMN). In this study, an understanding of the fabrication process was achieved by performing a DoE based on varying...

Full description

Saved in:
Bibliographic Details
Published in:Procedia manufacturing 2017, Vol.13, p.153-160
Main Authors: Carracedo-Taboada, M., O’Sullivan, Kathleen, McAuliffe, M.A.P., Vucen, S., O’Sullivan, C.
Format: Article
Language:English
Subjects:
calcium sulphate
design of experiments
micromoulding
Microneedles
self-setting ceramics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The paper presents the application of the factorial Design of Experiments (DoE) to evaluate the influence of process parameters on the physical characteristics of ceramic microneedles (CMN). In this study, an understanding of the fabrication process was achieved by performing a DoE based on varying two levels of five parameters. Statistical analyses were performed on the data to investigate whether the process parameters have a significant effect on the production of a patch of 25 microneedles (MN) with sharp tips. The study showed that four out of five main effects as well as an interaction between two parameters were significant.
ISSN:2351-9789
2351-9789
DOI:10.1016/j.promfg.2017.09.025