Undifferentiated sinonasal carcinoma may respond to single-fraction boron neutron capture therapy

A large, rapidly progressing, unresectable undifferentiated sinonasal head and neck carcinoma regressed rapidly following single fraction boron neutron capture therapy (BNCT). The main toxicity consisted of mucositis lasting for a few days. The quality of life improved and was excellent until tumour...

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Bibliographic Details
Published in:Radiotherapy and oncology 2004-07, Vol.72 (1), p.83-85
Main Authors: Kouri, Mauri, Kankaanranta, Leena, Seppälä, Tiina, Tervo, Leena, Rasilainen, Merja, Minn, Heikki, Eskola, Olli, Vähätalo, Jyrki, Paetau, Anders, Savolainen, Sauli, Auterinen, Iiro, Jääskeläinen, Juha, Joensuu, Heikki
Format: Article
Language:English
Subjects:
Adult
Boron Neutron Capture Therapy
Boronophenylalanine
Carcinoma - radiotherapy
Head and neck carcinoma
Humans
Male
Mucous Membrane - pathology
Paranasal Sinus Neoplasms - radiotherapy
Positron emission tomography
Quality of Life
Sinonasal carcinoma
Stomatitis - etiology
Treatment Outcome
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Summary:A large, rapidly progressing, unresectable undifferentiated sinonasal head and neck carcinoma regressed rapidly following single fraction boron neutron capture therapy (BNCT). The main toxicity consisted of mucositis lasting for a few days. The quality of life improved and was excellent until tumour recurrence 6 months after the date of BNCT.
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2004.03.016