Dosimetric parameters associated with radiation-induced esophagitis in breast cancer patients undergoing regional nodal irradiation

•We found that >15% of RNI patients developed symptomatic esophagitis.•IMRT use was associated with higher rates of esophagitis.•The esophagus OAR was systematically contoured from cricoid to carina.•We propose these esophageal OAR constraints: mean

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Bibliographic Details
Published in:Radiotherapy and oncology 2021-02, Vol.155, p.167-173
Main Authors: Yaney, Alexander, Ayan, Ahmet S., Pan, Xueliang, Jhawar, Sachin, Healy, Erin, Beyer, Sasha, Lindsey, Kylee, Kuhn, Karla, Tedrick, Kayla, White, Julia R., Bazan, Jose G.
Format: Article
Language:English
Subjects:
3DCRT
Breast cancer
Breast Neoplasms - radiotherapy
Esophagitis
Esophagitis - etiology
Humans
IMRT
LKB model
NTCP
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted
Radiotherapy, Conformal - adverse effects
Radiotherapy, Intensity-Modulated - adverse effects
Retrospective Studies
RNI
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Summary:•We found that >15% of RNI patients developed symptomatic esophagitis.•IMRT use was associated with higher rates of esophagitis.•The esophagus OAR was systematically contoured from cricoid to carina.•We propose these esophageal OAR constraints: mean
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2020.10.042