Levobupivacaine or ropivacaine: A randomised double blind controlled trial using equipotent doses in spinal anaesthesia

Levobupivacaine and ropivacaine are relatively new local anaesthetics developed in order to address the issue of bupivacaine toxicity. Although certain differences do exist between their pharmacological profiles, its clinical relevance at equipotent doses is not evident so far. To compare the effica...

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Bibliographic Details
Published in:Colombian journal of anesthesiology (Inglâes) 2016-04, Vol.44 (2), p.97-104
Main Authors: Athar, Manazir, Ahmed, Syed Moied, Ali, Shahna, Doley, Kashmiri, Varshney, Ankur, Siddiqi, Mohd. Masood Hussain
Format: Article
Language:English
Subjects:
Anestesia
Anestesia espinal
Anesthesia
Anesthesia, spinal
Anesthetics, local
Anestésicos locales
Bupivacaina
Bupivacaine
Hemodinámica
Hemodynamics
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Summary:Levobupivacaine and ropivacaine are relatively new local anaesthetics developed in order to address the issue of bupivacaine toxicity. Although certain differences do exist between their pharmacological profiles, its clinical relevance at equipotent doses is not evident so far. To compare the efficacy and characteristics of equipotent doses of intrathecal levobupivacaine with ropivacaine. Sixty ASA grade I/II patients of 18–60 years, either sex posted for lower limb orthopaedic surgery under spinal anaesthesia were randomly given either 15mg levobupivacaine or 22.5mg ropivacaine. Sensory and motor block, haemodynamic characteristics, as well as any side effects, were recorded. Onset of sensory block to T10 was more rapid in group R than group L, p
ISSN:2256-2087
DOI:10.1016/j.rcae.2016.02.012