Dyslipidemia and other cardiovascular risk factors in relation to manifest cardiovascular disease in patients with chronic obstructive pulmonary disease in the Canary Islands

• Published in: Revista clínica espanõla (English edition) 2020-06, Vol.220 (5), p.267-274
• Main Authors: Figueira Gonçalves, J.M., García Bello, M.A., Martín Martínez, M.D., García-Talavera, I., Mesa Fumero, J., García Hernández, S., Bethencourt Martín, N., Díaz Pérez, D., Afonso Díaz, A.
• Format: Article
• Language: English
• Subjects: Arterial hypertension; Chronic obstructive pulmonary disease; Comorbidities; Comorbilidades; Dislipemia; Dyslipidaemia; Enfermedad pulmonar obstructiva crónica; Hipertensión arterial
• ISSN: 2254-8874; 2254-8874
• DOI: 10.1016/j.rceng.2019.05.011

Cardiovascular disease has a negative impact on the vital prognosis of patients with chronic obstructive pulmonary disease (COPD), where dyslipidaemia (DLP) and arterial hypertension (AHT) are considered the most prevalent risk factors. The objective of this study was 1) to assess the relationship between diagnosed DLP and cardiovascular disease in COPD patients and compare it with other known cardiovascular risk factors and 2) to determine the relationship between the different cardiovascular comorbidities and the severity groups according to the GOLD 2017 classification. A cross-sectional, observational study was performed in 454 outpatients with COPD during their follow up. We calculated the prevalence of each of the cardiovascular comorbidities and the probability of each of the cardiovascular risk factors to occur jointly with a vascular disease (RRij). A total of 66.7% of the patients had DLP, whereby DLP was related to cerebrovascular accidents (CVA) (RRij 1.36, p = 0.0054), chronic kidney disease (CKD) (RRij 1.34, p = 0.00023), and peripheral arterial disease (PAD) (RRij 1.38, p = 0.00015). AHT was mostly related to CVA (RRij 1.41, p = 0.0014) and CKD (RRij 1.42, p