Clinical practice guideline for the treatment of psoriatic arthritis in Colombia

• Published in: Revista Colombiana de Reumatología (English Edition) 2023-07, Vol.30, p.S55-S64
• Main Authors: Fernández-Ávila, Daniel G., Arredondo González, Ana María, Arteaga, Carlos Ernesto, Jaramillo Arroyave, Daniel, Cortés Correa, Carolina Ivette, Chiquito, Susana, Castro-Ayarza, Juan Raul, Franco Franco, Manuel Darío, González Ardila, César Fernando, Londoño García, Ángela María, Martínez, Susan, Ibatá, Linda
• Format: Article
• Language: English
• Subjects: Artritis psoriásica; Guía de práctica; Practice guideline; Psoriatic arthritis; Tratamiento; Treatment
• ISSN: 2444-4405; 2444-4405
• DOI: 10.1016/j.rcreue.2023.02.007

Psoriatic arthritis is a chronic inflammatory arthropathy characterized by subtypes with distinct phenotypes and variable clinical course, which requires optimal management of joint manifestations and skin involvement. This study aims to provide recommendations for the pharmacological treatment of psoriatic arthritis based on evidence and applicability to the Colombian health system. These guidelines were developed according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology. Clinical experts, rheumatologists, and dermatologists formulated the recommendations based on clinical evidence, the disease's impact, patient values and preferences, and the resource availability in the country. The guideline includes 12 recommendations related to the use of anti-inflammatory drugs, glucocorticoids, and disease-modifying antirheumatic drugs (DMARDs), including conventional synthetics, biologics, and targeted synthetic DMARD, for the PsA domains: peripheral disease, axial disease, enthesitis, and dactylitis. This document presents a set of updated and evidence-based recommendations that guide decision-making about pharmacological management of psoriatic arthritis in adults in Colombia. They constitute general guidelines that should be interpreted and implemented according to the individualized evaluation of the patient and the medical criteria in the different clinical settings. La artritis psoriásica es una artropatía inflamatoria crónica con distintos fenotipos y curso clínico variable, que requiere un manejo óptimo de las manifestaciones articulares y del compromiso cutáneo. Este documento pretende hacer recomendaciones para el tratamiento farmacológico de la artritis psoriásica basadas en la evidencia y la aplicabilidad al sistema de salud colombiano. Estas guías fueron desarrolladas de acuerdo con la metodología Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Expertos clínicos, reumatólogos y dermatólogos formularon las recomendaciones con base en la evidencia clínica, el impacto de la enfermedad, los valores y las preferencias de los pacientes y la disponibilidad de recursos en el país. La guía incluye 12 recomendaciones relacionadas con el uso de antiinflamatorios, glucocorticoides y fármacos antirreumáticos modificadores de la enfermedad (FAME), incluidos los sintéticos convencionales, los biológicos y los sintéticos dirigidos, para los dominios de la artritis psoriásica: enfermedad perifér