Pronounced alterations in T-wave morphology during dipyridamole-induced ischemia

Abstract The case describes a 77-year-old woman with multivessel coronary disease exhibiting marked changes of T-wave morphology induced by dipyridamole, an unusual finding in which the diagnostic accuracy in this clinical context is uncertain. Gated-SPECT imaging demonstrated severe ischemia extend...

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Bibliographic Details
Published in:Revista Española de medicina nuclear e imagen molecular (English ed.) 2016-01, Vol.35 (1), p.42-45
Main Authors: Ferrando-Castagnetto, F, Ricca-Mallada, R, Ferrando-Castagnetto, R
Format: Article
Language:English
Subjects:
99mTc-MIBI SPECT
Bucle
Dipiridamol
Dipyridamole
Ischemia
Isquemia
Loop
Onda T
Radiology
T-wave
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Summary:Abstract The case describes a 77-year-old woman with multivessel coronary disease exhibiting marked changes of T-wave morphology induced by dipyridamole, an unusual finding in which the diagnostic accuracy in this clinical context is uncertain. Gated-SPECT imaging demonstrated severe ischemia extending through inferior and posterolateral regions of the left ventricle with normal motility and contractile function in response to vasodilator stress. Possible underlying mechanisms and clinical implications of observed electrocardiographic changes are discussed. T-loop modifications during vasodilator stress SPECT and correlation of these changes with the amount of ischemic injury need further evaluation.
ISSN:2253-8089
2253-8089
DOI:10.1016/j.remnie.2015.11.001