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Screening of Immunoglobulin E mediated Food Allergies among Children

Food allergy is a major public health concern all over the world. Data are lacking on the number of affected children, severity of food allergy, and burden of the disease. The current research aims at exploring the most common sensitization patterns of food allergy as well as collecting data on clin...

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Bibliographic Details
Published in:Revue française d'allergologie (2009) 2021-09, Vol.61 (5), p.345-350
Main Authors: Anani, M.M., El-Kelany, A.M., Hashem, A.A., Ahmed, S.H., Omar, H.H.
Format: Article
Language:English
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Summary:Food allergy is a major public health concern all over the world. Data are lacking on the number of affected children, severity of food allergy, and burden of the disease. The current research aims at exploring the most common sensitization patterns of food allergy as well as collecting data on clinical presentation among pediatrics. The sensitization pattern of the most common 21 food allergens through ImmunoLINE IgE Nutritional assay as well as total serum IgE test were assessed. The assessment was conducted on a group of 188 children aged from one to five years who visited the pediatric outpatient clinic of Suez Canal University hospital. One or more specific allergen components related IgE antibodies were found in 74.5% of the study participants. The mean level of total IgE in serum was 122.86 ±72.93 IU/ml. In addition, the percentage of children who were diagnosed with food allergy reached 22.3% whereas the percentage of those who were confirmed with food allergy was 4.3%. Furthermore, Egg yolk was represented as the most frequently food allergen with a percentage of 27.7% whereas egg white and cow milk amounted to 23.4%. Most of the children were found to be poly-sensitized. The frequent food allergies confirmed via ImmunoLINE IgE Nutritional assay were caused by cow's milk and egg yolk allergens. L’allergie alimentaire est un problème de santé publique majeur dans le monde entier. On manque de données sur le nombre d’enfants touchés, la gravité de l’allergie alimentaire et la charge de morbidité. La recherche actuelle vise à explorer les schémas de sensibilisation les plus courants de l’allergie alimentaire ainsi qu’à recueillir des données sur la présentation clinique en pédiatrie. Le profil de sensibilisation des 21 allergènes alimentaires les plus courants a été évalué par le test nutritionnel Immuno LINE IgE ainsi que par le test des IgE sériques totales. L’évaluation a été menée sur un groupe de 188 enfants âgés de un à cinq ans qui ont visité la clinique pédiatrique ambulatoire de l’hôpital universitaire du canal de Suez. Un ou plusieurs anticorps IgE spécifiques liés à des composants allergènes ont été trouvés chez 74,5 % des participants à l’étude. Le niveau moyen d’IgE total dans le sérum était de 122,86 ± 72,93 UI/ml. En outre, le pourcentage d’enfants chez qui une allergie alimentaire a été diagnostiquée a atteint 22,3 %, alors que le pourcentage de ceux chez qui une allergie alimentaire a été confirmée était de 4,3 %. En outre, le jaune
ISSN:1877-0320
1877-0320
DOI:10.1016/j.reval.2021.01.002