Successful treatment of pulmonary mucormycosis with combined medical and surgical approach

Mucormycosis is an invasive opportunistic fungal infection that occurs frequently in diabetic patients with high rate of mortality. We report a new case of pulmonary mucormycosis in a 56-year-old woman with poorly controlled insulin dependent type II diabetes. Initial symptoms were recurrent haemopt...

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Bibliographic Details
Published in:Respiratory medicine extra 2007, Vol.3 (3), p.120-123
Main Authors: Abid, Hanadi, Ammar, Jamel, Yengui, Ferdaous, Ayadi, Aida, Mezni, Faouzi, Mestiri, Tahar, Merghli, Adel, Jilani, Habiba, Hantous, Saoussen, Hamzaoui, Agnes
Format: Article
Language:English
Subjects:
Amphotericin B
Diabetes mellitus
Pulmonary mucormycosis
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Summary:Mucormycosis is an invasive opportunistic fungal infection that occurs frequently in diabetic patients with high rate of mortality. We report a new case of pulmonary mucormycosis in a 56-year-old woman with poorly controlled insulin dependent type II diabetes. Initial symptoms were recurrent haemoptysis with pulmonary infection unresponsive to broad-spectrum antibiotics. Bronchial biopsy showed hyphae with right-angle branching, typical of mucormycosis. Outcome was favourable after long-term amphotericin B and surgery. Although mucormycosis is rare, it should be considered in high-risk patients because early diagnosis and timely therapy combining antifungal drug, surgery and control of underlying disease appear to improve the prognosis.
ISSN:1744-9049
1744-9049
DOI:10.1016/j.rmedx.2007.05.007