Host–guest interaction of l-tyrosine with β-cyclodextrin

The inclusion complexes of β-cyclodextrin (β-CD) with l-tyrosine ( l-TYN) were investigated by using spectrophotometers. The absorption and fluorescence enhancement occurs with β-CD and l-TYN forms 1:1 inclusion complex. The unusual blue shift of hydroxyl ion in the β-CD medium confirms OH groups pr...

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Bibliographic Details
Published in:Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Molecular and biomolecular spectroscopy, 2008-11, Vol.71 (1), p.125-132
Main Authors: Shanmugam, M., Ramesh, D., Nagalakshmi, V., Kavitha, R., Rajamohan, R., Stalin, T.
Format: Article
Language:English
Subjects:
beta-Cyclodextrins - chemistry
Crystallization
Hydrogen-Ion Concentration
Hydroxyl Radical - chemistry
Inclusion complex
Ions
l-Tyrosine
Microscopy, Electron, Scanning
Models, Chemical
Oxygen - chemistry
pH effects
Powders
Protein Binding
Spectrometry, Fluorescence - methods
Spectrophotometry - methods
Spectroscopy, Fourier Transform Infrared
Thermodynamics
Tyrosine - chemistry
β-Cyclodextrin
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Summary:The inclusion complexes of β-cyclodextrin (β-CD) with l-tyrosine ( l-TYN) were investigated by using spectrophotometers. The absorption and fluorescence enhancement occurs with β-CD and l-TYN forms 1:1 inclusion complex. The unusual blue shift of hydroxyl ion in the β-CD medium confirms OH groups present in the interior part of the β-CD cavity and –COOH group present in the upper part of the β-CD cavity. A mechanism is proposed to explain inclusion process. The inclusion interaction was examined and the thermodynamic parameters of inclusion process Δ G, Δ H and Δ S were determined. The results indicated that the inclusion process was an exergonic and spontaneous process. Stable solid inclusion complexes were established and characterized by FT-IR, scanning electron microscope (SEM) methods.
ISSN:1386-1425
DOI:10.1016/j.saa.2007.10.054