UV–vis, IR and 1H NMR spectroscopic studies and characterization of ionic-pair crystal violet–oxytetracycline

The present study shows the formation and characterization of the ionic-pair between the antibiotic oxytetracycline and the dye crystal violet in ammonia solution pH 9.0 ± 0.2 extracted into chloroform. The characterization was demonstrated using UV–vis spectrophotometry, 1H NMR, measurement of rela...

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Bibliographic Details
Published in:Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Molecular and biomolecular spectroscopy, 2010, Vol.75 (1), p.437-443
Main Authors: Orellana, Sandra, Soto, César, Toral, M. Inés
Format: Article
Language:English
Subjects:
Characterization
Crystal violet
Ionic-pair
Oxytetracycline
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Summary:The present study shows the formation and characterization of the ionic-pair between the antibiotic oxytetracycline and the dye crystal violet in ammonia solution pH 9.0 ± 0.2 extracted into chloroform. The characterization was demonstrated using UV–vis spectrophotometry, 1H NMR, measurement of relaxation times T 1 and IR spectroscopy, using a comparison between the signals of individual pure compounds with the signals with the mixture CV–OTC in different alkaline media. The formation of ionic-pair was also corroborated by new signals and chemical shifts. (2D) NMR spectroscopy experiments show that the interaction is electrostatic.
ISSN:1386-1425
DOI:10.1016/j.saa.2009.11.002