PSS functionalized and stabilized carbon nanodots for specific sensing of iron in biological medium

[Display omitted] •Synthesis of CQD-PSS nanocomposite with stable fluorescence.•Polymer PSS not only stabilize the QDs but also produces specific sites for Fe3+.•The detection limit is as 1 ppm, adequate for measuring Fe3+ in blood or water samples.•The sensing process in presence of 1% BSA indicate...

Full description

Saved in:
Bibliographic Details
Published in:Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Molecular and biomolecular spectroscopy, 2023-05, Vol.293, p.122445, Article 122445
Main Authors: Ghosh, Malabika, Dasgupta, Uddipan, Nayek, Sumanta, Saha, Abhijit, Bhattacharjee, Rama Ranjan, Chowdhury, Ankan Dutta
Format: Article
Language:English
Subjects:
Biosensor
Ferric ions detection
Optical sensor
Selective
Stable quantum dots
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] •Synthesis of CQD-PSS nanocomposite with stable fluorescence.•Polymer PSS not only stabilize the QDs but also produces specific sites for Fe3+.•The detection limit is as 1 ppm, adequate for measuring Fe3+ in blood or water samples.•The sensing process in presence of 1% BSA indicates the stable performance in complex medium.•A possible optical probe for on-time iron detection in near future. Carbon Quantum Dots (CQDs) are already emerged as an excellent sensing element for its exceptional behavior in fluorescence, biocompatibility, and water dispersibility. However, its poor stability, selectivity and reproducibility in complex medium still be a big problem for its practical application. To overcome this, in the work, we have developed a new type of carbon quantum dot-PSS fluorescent nanocomposites which has been used for specific Fe3+ detection. The polystyrene sulfonate (PSS) polymer not only stabilize the QDs but also produces specific sites for Fe3+ to make a co-ordinate complex via Fe3+-SO3. The detection limit is calculated as low as 1 ppm which is adequate for measuring Fe3+ in blood or water samples. The mechanism of the quenching is very specific towards the Fe3+ ion due to the presence of PSS which makes the sensor selective among other metal ions and possible interferences. The rapid process of sensing, simple instrumentation, and excellent performances in presence of 1 % BSA and serum samples indicates the possible application for diagnostic usage in near future.
ISSN:1386-1425
DOI:10.1016/j.saa.2023.122445