Emodin, an antibacterial anthraquinone from the roots of Cassia occidentalis

The antibacterial activity of the ethanolic root extract of Cassia occidentalis was examined. A biologically active component was isolated and identified as emodin by spectroscopic analysis. The bioactive Minimum Inhibitory Concentration (MIC) values of emodin were 7.8 × 10 − 3 and 3.9 × 10 − 3 mg m...

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Bibliographic Details
Published in:South African journal of botany 2006-05, Vol.72 (2), p.295-297
Main Authors: Chukwujekwu, J.C., Coombes, P.H., Mulholland, D.A., van Staden, J.
Format: Article
Language:English
Subjects:
Antibacterial
Cassia occidentalis
Emodin
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Summary:The antibacterial activity of the ethanolic root extract of Cassia occidentalis was examined. A biologically active component was isolated and identified as emodin by spectroscopic analysis. The bioactive Minimum Inhibitory Concentration (MIC) values of emodin were 7.8 × 10 − 3 and 3.9 × 10 − 3 mg ml − 1 against Bacillus subtilis and Staphylococcus aureus, respectively. It was not active against two Gram-negative bacteria ( Klebsiella pneumoniae and Escherichia coli) at the highest concentration (5.0 × 10 − 1 mg ml − 1 ) tested.
ISSN:0254-6299
1727-9321
DOI:10.1016/j.sajb.2005.08.003