Co-occurrence of phthalate esters and perfluoroalkyl substances affected bacterial community and pathogenic bacteria growth in rural drinking water distribution systems

• Published in: The Science of the total environment 2023-01, Vol.856 (Pt 1), p.158943, Article 158943
• Main Authors: Yin, Hong, Chen, Ruya, Wang, Haibo, Schwarz, Cory, Hu, Haotian, Shi, Baoyou, Wang, Yili
• Format: Article
• Language: English
• Subjects: Bacteria; Bacterial community; Dibutyl Phthalate - analysis; Drinking Water; Esters - analysis; Fluorocarbons - toxicity; Human diseases; Humans; Microbiological risks; PAEs; PFAS; Potential human pathogenic bacteria
• ISSN: 0048-9697; 1879-1026
• DOI: 10.1016/j.scitotenv.2022.158943

The adverse health effects of phthalate esters (PAEs) and perfluoroalkyl substances (PFAS) in drinking water have attracted considerable attention. Our study investigated the effects of PAEs and PFAS on the bacterial community and the growth of potential human pathogenic bacteria in rural drinking water distribution systems. Our results showed that the total concentration of PAEs and PFAS ranged from 1.02 × 102 to 1.65 × 104 ng/L, from 4.40 to 1.84 × 102 ng/L in rural drinking water of China, respectively. PAEs concentration gradually increased and PFAS slowly decreased along the pipeline distribution, compared to concentrations in the effluents of rural drinking water treatment plants. The co-occurrence of higher concentrations of PAEs and PFAS changed the structure and function of the bacterial communities found within these environments. The bacterial community enhanced their ability to respond to fluctuating environmental conditions through up-regulation of functional genes related to extracellular signaling and interaction, as well as genes related to replication and repair. Under these conditions, co-occurrence of PAEs and PFAS promoted the growth of potential human pathogenic bacteria (HPB), therefore increasing the risk of the development of associated diseases among exposed persons. The main HPB observed in this study included Burkholderia mallei, Mycobacterium tuberculosis, Klebsiella pneumoniae, Acinetobacter calcoaceticus, Escherichia coli, and Pseudomonas aeruginosa. Contaminants including particles, microorganisms, PAEs and PFAS were found to be released from corrosion scales and deposits of pipes and taps, resulting in the increase of the cytotoxicity and microbial risk of rural tap water. These results are important to efforts to improve the safety of rural drinking water. [Display omitted] •PAEs, PFASs and bacteria were investigated in rural drinking water of China.•PAEs concentration increased and PFASs decreased along the distribution of pipes.•PAEs and PFASs changed the bacterial community composition and their function.•PFOA, PFOS, PFBA, PFHxS, DEHP, DBP and DIBP promoted pathogenic bacteria growth.•Release of contaminants from deposits promoted microbial risk of rural tap water.