Detection of protein aggregation with a Bloch surface wave based sensor

We present the innovative application of a Bloch surface wave based sensor to the detection of protein aggregation. In Hen Egg White Lysozyme (HEWL) solutions, aggregates are discriminated from the monomeric forms in a label-free detection scheme.

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Bibliographic Details
Published in:Sensors and actuators. B, Chemical Chemical, 2011-09, Vol.157 (1), p.260-264
Main Authors: Paeder, V., Musi, V., Hvozdara, L., Herminjard, S., Herzig, H.P.
Format: Article
Language:English
Subjects:
Bloch Surface Waves (BSW)
Optical sensor
Protein aggregation
Protein detection
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Description
Summary:We present the innovative application of a Bloch surface wave based sensor to the detection of protein aggregation. In Hen Egg White Lysozyme (HEWL) solutions, aggregates are discriminated from the monomeric forms in a label-free detection scheme.
ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2011.03.060