A new highly selective chemosensor for the detection of iron ion in aqueous medium based on click generated triazole

• Published in: Sensors and actuators. B, Chemical Chemical, 2017-10, Vol.249, p.515-522
• Main Authors: Shah, Kiramat, Ain, Noor ul, Ahmed, Farid, Anis, Itrat, Shah, Muhammad Raza
• Format: Article
• Language: English
• Subjects: Absorption intensity; Chemosensor; Interference; Stoichiometry; Triazole
• ISSN: 0925-4005; 1873-3077
• DOI: 10.1016/j.snb.2017.04.120

•New triazole based molecular probe 5 was synthesized and characterized.•The probe exhibited excellent selectivity and sensitivity for Fe+3 in Acetone/H2O.•UV–vis, 1H NMR, FT-IR and mass spectroscopic techniques were used for the evaluation of photophysical properties.•The binding stoichiometry is determined by Job’s plot method. A new click generated triazole based chemosensor 5 was designed and synthesized, that exhibits excellent selectivity for Fe+3 ion over a wide range of tested metal ions e.g. NH4+, Li+, Na+, K+, Cu+, Ag+, Ca+2, Ni+2, Co+2, Cd+2, Mg+2, Cu+2, Zn+2, Pb+2, Hg+2, In+3, La+3and Y+3 in an aqueous medium without any remarkable interference. With Fe+3, the sensor 5 showed enhancement in absorption intensity at wavelength of 262nm. The sensor forms a host-guest complex in 1:1 stoichiometry with the detection limit down to 3.21μM. The interaction was also confirmed by FT-IR, 1H NMR and FAB showing the Sensor 5–Fe+3 adduct at 495. Further, the sensor was successfully utilized to detect Fe+3 in human blood plasma and laboratory tap water as well.