Magnetite-doped nanopowder boron nitride for 10B delivery agent in BNCT

Several chemical routes are proposed for the synthesis of hexagonal boron nitride h-BN nanopowders doped with magnetic nanoclusters – ferromagnetic iron Fe or ferrimagnetic magnetite Fe3O4. Nanocomposites obtained during our experiments reveal magnetic properties rendering them useful for an applica...

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Bibliographic Details
Published in:Solid state sciences 2024-08, Vol.154, p.107614, Article 107614
Main Authors: Makatsaria, Shio, Chkhartishvili, Levan, Barbakadze, Natia, Tsagareishvili, Otar, Kekutia, Shalva, Markhulia, Jano, Mikelashvili, Vladimer, Mirzayev, Matlab, Jinikashvili, Irma, Oboladze, Shota, Chedia, Roin
Format: Article
Language:English
Subjects:
BNCT
Boron nitride
Delivery agent
Deposition
Intercalation
Magnetic cluster
Magnetic properties
Nanopowder
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Summary:Several chemical routes are proposed for the synthesis of hexagonal boron nitride h-BN nanopowders doped with magnetic nanoclusters – ferromagnetic iron Fe or ferrimagnetic magnetite Fe3O4. Nanocomposites obtained during our experiments reveal magnetic properties rendering them useful for an application in BNCT (Boron Neutron Capture Therapy) for external magnetic field controlled delivery of neutron-capturing boron 10B isotopes in target tumor cells. [Display omitted] •Nanostructured hexagonal boron nitride doped with magnetite h-BN–Fe3O4 can be used for effective delivery agent in BNCT.•There are developed chemical synthesis routes for obtaining h-BN–Fe3O4 composites in nanopowder form.•There are studied room-temperature magnetic properties of obtained h-BN–Fe3O4 composites.
ISSN:1293-2558
1873-3085
DOI:10.1016/j.solidstatesciences.2024.107614