Supercritical fluids applications in nanomedicine

•This review critically analyses supercritical fluid processes for medical application.•Nanoparticles, nanostructured microparticles and nanoporous materials are reviewed.•Future perspectives of supercritical processes in nanomedicine are considered. Nanomedicine consists of the application of nanot...

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Bibliographic Details
Published in:The Journal of supercritical fluids 2015-06, Vol.101, p.193-214
Main Authors: Campardelli, R., Baldino, L., Reverchon, E.
Format: Article
Language:English
Subjects:
Nanocarriers
Nanomedicine
Nanoparticles
Nanoporous materials
Nanostructured
Supercritical fluids
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Summary:•This review critically analyses supercritical fluid processes for medical application.•Nanoparticles, nanostructured microparticles and nanoporous materials are reviewed.•Future perspectives of supercritical processes in nanomedicine are considered. Nanomedicine consists of the application of nanotechnologies in the medical field. In many nanomedical applications, supercritical fluids based processes represent the best potential choice, since they allow controlled fabrication of biological active nanoparticles, nanostructured microparticles, nanoporous/nanostructured materials. These products can be used to develop cell diagnostic kits, intracellular devices, engineered drug delivery systems, implantable materials and devices. This review is a critical analysis of the results reported in the literature on this fascinating and explosively growing field.
ISSN:0896-8446
1872-8162
DOI:10.1016/j.supflu.2015.01.030