Synthesis of new unsymmetrical polyarylester dendrimers

Preparation of polyarylester dendrimers containing 2-(hydroxymethyl)-1,4-butanediol and 2,2-bis(hydroxymethyl)-1,4-butanediol cores is described. These polyarylester dendrimers are unsymmetrical with respect to chain lengths and function as model systems for studying in vitro controlled drug release...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron 2004-04, Vol.60 (17), p.3739-3744
Main Authors: Potluri, Srinagesh Kumar, Raghu Ramulu, A, Pardhasaradhi, M
Format: Article
Language:English
Subjects:
Convergent-divergent approach
Dendrimers
Dendritic wedge
Polyaryl ester
Trichloroethyl protection
Unsymmetrical
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Preparation of polyarylester dendrimers containing 2-(hydroxymethyl)-1,4-butanediol and 2,2-bis(hydroxymethyl)-1,4-butanediol cores is described. These polyarylester dendrimers are unsymmetrical with respect to chain lengths and function as model systems for studying in vitro controlled drug release systems. Reaction conditions for deprotection of trichloroethyl group of the dendritic wedges have been improved. Graphic
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2004.03.024