A convenient microwave-assisted 5-amination of flavones

A few examples of 5-aminoflavones' syntheses exist in the literature and for those, which are described, the amino group is introduced before the formation of the flavone skeleton. We describe here an efficient method, which permits the access to 5-aminoflavones by a simple procedure using an S...

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Bibliographic Details
Published in:Tetrahedron 2008-12, Vol.64 (49), p.11243-11248
Main Authors: Lecoutey, Cédric, Fossey, Christine, Demuynck, Luc, Lefoulon, François, Fabis, Frédéric, Rault, Sylvain
Format: Article
Language:English
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Summary:A few examples of 5-aminoflavones' syntheses exist in the literature and for those, which are described, the amino group is introduced before the formation of the flavone skeleton. We describe here an efficient method, which permits the access to 5-aminoflavones by a simple procedure using an SNAr amination under microwaves irradiation. [Display omitted]
ISSN:0040-4020
1464-5416
DOI:10.1016/j.tet.2008.09.043