Design and synthesis of a novel neo-glycolipid containing sialyl Lewis X determinant carried on the mucin GlcNAcβ1-6GalNAcα core structure

[Display omitted] A novel neo-glycolipid containing sialyl Lewis X determinant carried on the mucin GlcNAcβ1-6GalNAcα core structure has been designed and synthesized. By employing this compound as a probe, the structure required for the recognition of anti-cancer antibodies, NCC-ST-439, has been el...

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Bibliographic Details
Published in:Tetrahedron: asymmetry 2005-04, Vol.16 (7), p.1321-1327
Main Authors: Otsubo, Nobumasa, Ishida, Hideharu, Kannagi, Reiji, Kiso, Makoto
Format: Article
Language:English
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Summary:[Display omitted] A novel neo-glycolipid containing sialyl Lewis X determinant carried on the mucin GlcNAcβ1-6GalNAcα core structure has been designed and synthesized. By employing this compound as a probe, the structure required for the recognition of anti-cancer antibodies, NCC-ST-439, has been elucidated.
ISSN:0957-4166
1362-511X
DOI:10.1016/j.tetasy.2005.02.013