C-Phosphanylated sulfoximines: synthesis and applications in asymmetric allylic substitution reactions

Starting from cyclic sulfonimidates, a number of C-phosphanylated enantiomerically pure sulfoximines have been prepared either as such or in protected form. Two of them, 5a and epi- 5a, have been used as ligands in palladium complex catalyzed allylic substitution reactions delivering the substitutio...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron: asymmetry 2006-02, Vol.17 (4), p.500-503
Main Authors: Spohr, Volker, Kaiser, Jan Philipp, Reggelin, Michael
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Starting from cyclic sulfonimidates, a number of C-phosphanylated enantiomerically pure sulfoximines have been prepared either as such or in protected form. Two of them, 5a and epi- 5a, have been used as ligands in palladium complex catalyzed allylic substitution reactions delivering the substitution product with up to 95% ee.
ISSN:0957-4166
1362-511X
DOI:10.1016/j.tetasy.2006.01.008