Synthesis of N-alkylanthranilamides with a chiral substituent at the nitrogen atom

Novel anthranilamides containing a chiral substituent at the nitrogen atom and different substituents on the benzene ring were prepared from the corresponding isatins in good yields and high enantioselectivities (up to 98%).

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Bibliographic Details
Published in:Tetrahedron: asymmetry 2010-09, Vol.21 (17), p.2100-2107
Main Authors: Kurkin, Alexander V., Bernovskaya, Anna A., Yurovskaya, Marina A.
Format: Article
Language:English
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Description
Summary:Novel anthranilamides containing a chiral substituent at the nitrogen atom and different substituents on the benzene ring were prepared from the corresponding isatins in good yields and high enantioselectivities (up to 98%).
ISSN:0957-4166
1362-511X
DOI:10.1016/j.tetasy.2010.07.001