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Iodine-catalyzed highly efficient Michael reaction of indoles under solvent-free condition

A new iodine-catalyzed remarkably simple Michael reaction of indoles with enones was developed. Michael reaction of indoles with unsaturated ketones has been accomplished in the presence of catalytic amount of iodine under solvent-free condition.

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Bibliographic Details
Published in:Tetrahedron letters 2005-04, Vol.46 (14), p.2479-2482
Main Authors: Banik, Bimal K., Fernandez, Miguel, Alvarez, Clarissa
Format: Article
Language:English
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Summary:A new iodine-catalyzed remarkably simple Michael reaction of indoles with enones was developed. Michael reaction of indoles with unsaturated ketones has been accomplished in the presence of catalytic amount of iodine under solvent-free condition.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2005.02.044