Catalytic enantioselective fluorination of α-cyano acetates catalyzed by chiral palladium complexes

[Display omitted] The catalytic enantioselective electrophilic fluorination promoted chiral palladium complexes is described. Treatment of α-cyano acetates with N-fluorobenzenesulfonimide as the fluorine source under mild reaction conditions afforded the corresponding α-cyano α-fluoro acetates in hi...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2005-04, Vol.46 (17), p.3115-3117
Main Authors: Kim, Hye Ran, Kim, Dae Young
Format: Article
Language:English
Subjects:
Asymmetric reactions
Chiral palladium complexes
Fluorination
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] The catalytic enantioselective electrophilic fluorination promoted chiral palladium complexes is described. Treatment of α-cyano acetates with N-fluorobenzenesulfonimide as the fluorine source under mild reaction conditions afforded the corresponding α-cyano α-fluoro acetates in high yields with excellent enantiomeric excesses (85–99% ee).
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2005.02.164