Regioselective synthesis of functionally congested biaryls through a novel C–C bond formation reaction

[Display omitted] An expeditious synthesis of unsymmetrical biaryls functionalized with electron-withdrawing or -donating substituents is described and illustrated by the carbanion-induced ring transformation of 2 H-pyran-2-ones with malononitrile in excellent yields.

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2005-08, Vol.46 (33), p.5585-5587
Main Authors: Goel, Atul, Singh, Fateh Veer
Format: Article
Language:English
Subjects:
Biaryl
Lactone
Malononitrile
Phenyl acetone
Pyran-2-one
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[Display omitted] An expeditious synthesis of unsymmetrical biaryls functionalized with electron-withdrawing or -donating substituents is described and illustrated by the carbanion-induced ring transformation of 2 H-pyran-2-ones with malononitrile in excellent yields.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2005.06.034