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Efficient synthesis of arylsulfamides by reaction of amines with arylsulfamoyl imidazolium triflate
Arylsulfamoyl imidazolium triflates, readily prepared from the corresponding chlorides, react with amines under neutral conditions to form arylsulfamides in high yields. This methodology, which contrasts with the slow and inefficient reactions of amines with arylsulfamoyl chlorides, is applied to th...
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Published in: | Tetrahedron letters 2005-10, Vol.46 (42), p.7139-7142 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Arylsulfamoyl imidazolium triflates, readily prepared from the corresponding chlorides, react with amines under neutral conditions to form arylsulfamides in high yields. This methodology, which contrasts with the slow and inefficient reactions of amines with arylsulfamoyl chlorides, is applied to the synthesis of arylsulfamide
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, a bioisotere of muraglitazar. |
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ISSN: | 0040-4039 1873-3581 |
DOI: | 10.1016/j.tetlet.2005.08.092 |