Parallel synthesis of N-arylpiperazines using polymer-assisted reactions

A series of N-arylpiperazines were prepared in a parallel fashion using palladium-catalyzed cross-coupling, or nucleophilic aromatic displacement chemistries, and polymer-assisted sequestration and purification techniques as key steps. A series of N-arylpiperazines were prepared in a parallel fashio...

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Bibliographic Details
Published in:Tetrahedron letters 2006-04, Vol.47 (15), p.2549-2552
Main Authors: Duncton, Matthew A.J., Roffey, Jonathan R.A., Hamlyn, Richard J., Adams, David R.
Format: Article
Language:English
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Summary:A series of N-arylpiperazines were prepared in a parallel fashion using palladium-catalyzed cross-coupling, or nucleophilic aromatic displacement chemistries, and polymer-assisted sequestration and purification techniques as key steps. A series of N-arylpiperazines were prepared in a parallel fashion using palladium-catalyzed cross-coupling, or nucleophilic aromatic displacement chemistries, and polymer-assisted sequestration and purification techniques as key steps.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2006.02.047