Lactones from lactones: regio and diastereoselective double dinucleophilic additions of bis(OTMS) ketene acetals to pyridines

Lactones from lactones: a cascade transformation is observed during two successive double nucleophilic additions of bis (TMS) ketene acetals to pyridines.

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Bibliographic Details
Published in:Tetrahedron letters 2006-07, Vol.47 (27), p.4541-4544
Main Authors: Xu, Yiming, Rudler, Henri, Denise, Bernard, Parlier, Andrée, Chaquin, Patrick, Herson, Patrick
Format: Article
Language:English
Subjects:
Dihydropyridines
Ketene acetals
Lactone
Nucleophilic additions
Piperidines
Tetrahydropyridines
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Description
Summary:Lactones from lactones: a cascade transformation is observed during two successive double nucleophilic additions of bis (TMS) ketene acetals to pyridines.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2006.05.004