Microwave-assisted synthesis of 1,3-dihydro-[1,2,5]thiadiazolo[3,4- b]pyrazine-2,2-dioxides

1,3-Dihydro[1,2,5]thiadiazolo[3,4- b]pyrazine-2,2-dioxides are obtained in a good yield from the reaction of 2,3-diamino pyrazines with sulfamide under microwave conditions. 1,3-Dihydro[1,2,5]thiadiazolo[3,4- b]pyrazine-2,2-dioxides are obtained in a good yield from the reaction of 2,3-diamino pyraz...

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Bibliographic Details
Published in:Tetrahedron letters 2006-11, Vol.47 (48), p.8603-8606
Main Authors: Sevilla, Sara, Forns, Pilar, Fernàndez, Joan-Carles, de la Figuera, Natalia, Eastwood, Paul, Albericio, Fernando
Format: Article
Language:English
Subjects:
Microwave
Nucleophilic aromatic substitution
Sulfonylureas
Suzuki reaction
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Summary:1,3-Dihydro[1,2,5]thiadiazolo[3,4- b]pyrazine-2,2-dioxides are obtained in a good yield from the reaction of 2,3-diamino pyrazines with sulfamide under microwave conditions. 1,3-Dihydro[1,2,5]thiadiazolo[3,4- b]pyrazine-2,2-dioxides are obtained in a good yield from the reaction of 2,3-diamino pyrazines with sulfamide under microwave conditions.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2006.09.097