Microwave-assisted three component one-pot synthesis of pyrimido-oxazepines

A synthetic approach toward pyrimido-oxazepine analogs was developed through the use of microwave heating. Certain analogs can be made in one step, which make this a valuable tool in the investigation of this therapeutically relevant scaffold.

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Bibliographic Details
Published in:Tetrahedron letters 2007-02, Vol.48 (8), p.1489-1492
Main Authors: Hudson, Colleen, Srinivasa Murthy, V., Estep, Kimberly G., Gustafson, Gary
Format: Article
Language:English
Subjects:
Microwave
Oxazepines
Three component reaction
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Description
Summary:A synthetic approach toward pyrimido-oxazepine analogs was developed through the use of microwave heating. Certain analogs can be made in one step, which make this a valuable tool in the investigation of this therapeutically relevant scaffold.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2006.12.058