A novel system for the synthesis of nitriles from aldehydes using aqueous ammonia and sodium dichloroiodate

A simple and mild method for the conversion of varieties of aldehydes to the corresponding nitriles using aqueous ammonia and aqueous sodium dichloroiodate reagent at room temperature is discussed. Advantages of this system are short reaction time, easy work-up and moderate to good yields.

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Bibliographic Details
Published in:Tetrahedron letters 2008-03, Vol.49 (14), p.2213-2215
Main Authors: Telvekar, Vikas N., Patel, Kavit N., Kundaikar, Harish S., Chaudhari, Hemchandra K.
Format: Article
Language:English
Subjects:
Aldehydes
Aqueous ammonia
Nitriles
Sodium dichloroiodate solution
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Description
Summary:A simple and mild method for the conversion of varieties of aldehydes to the corresponding nitriles using aqueous ammonia and aqueous sodium dichloroiodate reagent at room temperature is discussed. Advantages of this system are short reaction time, easy work-up and moderate to good yields.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2008.02.046