Diastereoselective synthesis of spiro-functionalized tetraalkyl benzoisoquinopyrrolonaphthyridine-tetracarboxylates from isoquinoline, dialkyl acetylenedicarboxylates, and indane-1,3-dione

An effective route to spiro-functionalized fused polycyclic derivatives of isoquinoline is described via tandem reaction of isoquinoline, dialkyl acetylenedicarboxylates, and indane-1,3-dione.

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Bibliographic Details
Published in:Tetrahedron letters 2010-01, Vol.51 (2), p.396-398
Main Authors: Yavari, Issa, Mirzaei, Anvar, Moradi, Loghman, Khalili, Gholamhossein
Format: Article
Language:English
Subjects:
Acetylenic esters
Indane-1,3-dione
Isoquinoline
Spiro compound
Tandem reaction
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Description
Summary:An effective route to spiro-functionalized fused polycyclic derivatives of isoquinoline is described via tandem reaction of isoquinoline, dialkyl acetylenedicarboxylates, and indane-1,3-dione.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2009.11.040