A mild and convenient synthesis of quinoxalines via cyclization–oxidation process using DABCO as catalyst

An efficient and general method has been described for the synthesis of quinoxalines by the reaction of 1,2-diamines with phenacyl bromides in the presence of DABCO. The method is suitable for the preparation of functionalized quinoxalines.

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Bibliographic Details
Published in:Tetrahedron letters 2010-05, Vol.51 (19), p.2580-2585
Main Authors: Meshram, H.M., Santosh Kumar, G., Ramesh, P., Chennakesava Reddy, B.
Format: Article
Language:English
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Description
Summary:An efficient and general method has been described for the synthesis of quinoxalines by the reaction of 1,2-diamines with phenacyl bromides in the presence of DABCO. The method is suitable for the preparation of functionalized quinoxalines.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2010.01.107