Pseudo four-component synthesis of benzopyranopyrimidines

An efficient and simple method for the synthesis of new benzopyranopyrimidines via a pseudo four-component reaction of salicylic aldehydes, malononitrile and various amines in the presence of a catalytic amount of LiClO 4 is reported. The advantages of this procedure are mild reaction conditions, hi...

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Bibliographic Details
Published in:Tetrahedron letters 2010-08, Vol.51 (32), p.4202-4204
Main Authors: Ghahremanzadeh, Ramin, Amanpour, Tayebeh, Bazgir, Ayoob
Format: Article
Language:English
Subjects:
Benzopyranopyrimidine
Malononitrile
Multicomponent
Salicylaldehyde
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Summary:An efficient and simple method for the synthesis of new benzopyranopyrimidines via a pseudo four-component reaction of salicylic aldehydes, malononitrile and various amines in the presence of a catalytic amount of LiClO 4 is reported. The advantages of this procedure are mild reaction conditions, high yields of products and operational simplicity.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2010.06.014