γ-Alumina as a recyclable catalyst for the four-component synthesis of 6-amino-4-alkyl/aryl-3-methyl-2,4-dihydropyrano[2,3- c]pyrazole-5-carbonitriles in aqueous medium

γ-Alumina as an expedient and recyclable catalyst for the synthesis of 6-amino-4-alkyl/aryl-3-methyl-2,4-dihydropyrano[2,3- c]pyrazole-5-carbonitriles in water via a four-component reaction is established. Comparative study of the efficacy of γ-alumina, basic alumina and KF-alumina is also discussed...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2011-05, Vol.52 (19), p.2523-2525
Main Authors: Mecadon, Hormi, Rohman, Md. Rumum, Rajbangshi, Mantu, Myrboh, Bekington
Format: Article
Language:English
Subjects:
Catalysis
Catalysts: preparations and properties
Chemistry
Exact sciences and technology
Four-component reaction
General and physical chemistry
Heterocyclic compounds
Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms
Organic chemistry
Preparations and properties
Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry
Water
γ-Alumina
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:γ-Alumina as an expedient and recyclable catalyst for the synthesis of 6-amino-4-alkyl/aryl-3-methyl-2,4-dihydropyrano[2,3- c]pyrazole-5-carbonitriles in water via a four-component reaction is established. Comparative study of the efficacy of γ-alumina, basic alumina and KF-alumina is also discussed. The method presented is mild, environment friendly, inexpensive and functionality tolerable to give the products in good to excellent yields.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2011.03.036