Microwave promoted catalyst-free benzylic C–H functionalization of methyl quinoline and Michael addition to beta-nitro styrene

A catalyst-free aqueous mediated C–H activation of methyl quinolines and addition to various beta-nitro styrenes were executed under Microwave irradiation. Catalyst-free, additive free, simple workup, clean reaction conditions, easy isolation and environmentally benign medium are the best features o...

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Bibliographic Details
Published in:Tetrahedron letters 2013-03, Vol.54 (10), p.1315-1317
Main Authors: Nageswara Rao, N., Meshram, H.M.
Format: Article
Language:English
Subjects:
Catalyst-free conditions
Methyl quinoline
Microwave
Nitro styrene
Water
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Summary:A catalyst-free aqueous mediated C–H activation of methyl quinolines and addition to various beta-nitro styrenes were executed under Microwave irradiation. Catalyst-free, additive free, simple workup, clean reaction conditions, easy isolation and environmentally benign medium are the best features of the present protocol.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2013.01.007